The Holy Roman Emperor Frederick II Hohenstaufen leaves the Holy Land though Pope Gregory IX had wanted him to stay to secure everything. His disobedience prompted the Holy Father to excommunicate the German king.
Death of King Albert I of Habsburg of Germany, murdered by his disinherited nephew Charles of Valois.
Coronation of King Edward Bruce coronated as King of Ireland.
Death of Saint Peregrine Laziosi, a Servite priest and healer of cancer to which he is the patron saint of cancer victims.
Death of Pope Saint Pius V, 225th successor of Peter and one of the great pontiffs in Church annals. Pius carried out the decrees of the Council of Trent and decreed the use of the Roman Missal.
Death of Saint Athanasius, Archbishop of Alexandria, Eygpt and Doctor of the Church.
Death of Leonardo da Vinci, master painter extraordinaire known most for his famous "Last Supper" painting.
The Catholic Queen of Scots Mary Stuart escapes from Loch Leven.
Pope Saint Gelasius I decrees that his spiritual power as supreme pontiff is superior to the temporal power of the Emperor Anastasius. It was called the Gelasian Decree.
Death of Saint Theodosius Pechersky, Abbot and founder of Russian monasticism who died in the Caves of Kiev.
The Papal/Genoese fleet is captured by Imperial ships of Emperor Frederick and Pope Gregory IX, near death, is helpless to come to their aid.
The Fifth Lateran Council, known as the 18th Ecumenical Council, is convened by Pope Julius II in Rome with reforms on the agenda which would be rebuked by Martin Luther and others spawning the Protestant Reformation.